Bombyx mori nucleopolyhedrovirus (BmNPV) is the pathogen of silkworm nuclear polyhedrosis. The BmNPV is a baculoviruses belonging to the dsDNA viruses Class, Baculoviridae Family and Alphabaculovirus Genus. The BmNPV can cause silkworm severe and acute disease resulting in large-scale death and great economic losses.