Silkworm transcriptome response to microsporidian infection

The silkworm Bombyx mori was infected by purified Nosema bombycis CQ1 so that a genome-wide transcriptional profile was investigated by the silkworm 23K genome array. Using a 2.0-fold cut-off, the transcription level of 2,691 genes (ca. 18.8% of total genes) was significantly altered between 2 and 8 dpi (see the table). The data can be queried by probe ID, gene ID or gene annotation. Values in the column marked by “2dpi”, “4dpi”, “6dpi” and “8dpi” show the fold change value (ratio of experimental and normal fluorescence value) of genes at 2, 4, 6 and 8 days post infection, respectively. Only when the fold change value is ≥2 or ≤0.5 were genes considered to be up- or down-regulated in compared with control. In total, this dataset can be a reference and be applied to analyze the N. bombycis-specific response of silkworm [1].

  1. Zhengang Ma, Chunfeng Li, Guoqing Pan, et al. Genome-Wide Transcriptional Response of Silkworm (Bombyx mori) to Infection by the Microsporidian Nosema bombycis. PLoS One. 2013, 8(12):e84137. doi:10.1371/journal.pone.0084137. eCollection 2013.