Silkworm transcriptome response to bacteria infection

Bacillus bombysepticus (Bb) is a natural pathogen of silkworm Bombyx mori and can cause silkworm acute fuliginosa septicaemia. Silkworm gene expressions at 3, 6, 12 and 24 hours post Bb infection were investigated with microarray. Genome-wide survey of the silworm genes demonstrated that many genes and pathways, including genes involved in juvenile hormone synthesis, metabolism and immnue were modulated after the infection [1].

  1. Huang L, Cheng T, Xu P, et al. A genome-wide survey for host response of silkworm, Bombyx mori during pathogen Bacillus bombyseptieus. PLoS One. 2009, 4(12):e8098. doi: 10.1371/journal.pone.0008098..